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Updated: Apr 5, 2026

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Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand

Joseph Y Kim1, Arumugam Balamurugan2, Kodi Azari3

  • 1Division of Infectious Diseases, Department of Medicine, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America; Department of Microbiology, Immunology, and Molecular Genetics, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

Plos One
|August 20, 2015
PubMed
Summary

Transplant rejection involves specific T cell receptor (TCR) clones, primarily using limited TCR beta chain variable (BV) gene families. Understanding these clonal populations may enable targeted immunotherapies for transplant recipients.

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