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Pentazocine-induced contractures: Dilemma in management
Dileep Kumar1, Anil Gupta1, V P Sharma1
1Department of Physical Medicine and Rehabilitation, King George Medical University, Lucknow, Uttar Pradesh, India.
Indian Journal of Pharmacology
|August 20, 2015
Summary
This case report details a rare instance of pentazocine (Fortwin) abuse in a 32-year-old female. The abuse led to severe myogenic contractures of her knee joints, highlighting potential complications of opioid use.
Area of Science:
- Pharmacology
- Clinical Case Study
- Toxicology
Background:
- Pentazocine is a widely prescribed synthetic opioid analgesic for managing moderate to severe pain.
- Parenteral opioid abuse is associated with known complications such as skin ulcerations, abscesses, indurations, and sclerosis.
Observation:
- A rare case of pentazocine (Fortwin) abuse presented in a 32-year-old female patient.
- The patient exhibited severe myogenic contractures affecting her knee joints.
Findings:
- This case highlights an unusual presentation of pentazocine abuse.
- The drug abuse resulted in significant musculoskeletal complications, specifically knee joint contractures.
Implications:
- This case underscores the importance of monitoring for substance abuse in patients presenting with unusual or severe complications.
- Healthcare providers should be aware of the potential for rare, severe musculoskeletal complications arising from pentazocine abuse.
- Further research may be warranted to understand the specific mechanisms linking pentazocine abuse to myogenic contractures.
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