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Updated: Apr 5, 2026

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
Published on: May 10, 2022
What does the pharmacological future of treating chronic hepatitis C look like?
Emily L Heil1, Lauren M Hynicka, Shyam Kottilil
1a 1 Department of Pharmacy, University of Maryland Medical Center, 29 S. Greene St, Room 400, Baltimore, MD 21201, USA.
Abstract:
Development of direct acting antivirals has revolutionized the standard of care for the treatment of hepatitis C virus. New interferon-free regimens provide sustained virologic response rates of >90% in many genotype 1 patients with only 12 weeks of oral therapy. This review will provide a brief overview of current standards of care with a summary of the evidence supporting the recommended combinations of direct acting antivirals. We will discuss the direction of future therapies, with strategies for shorter durations of therapy and new all-oral combinations in the pipeline.
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