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Updated: Apr 5, 2026

In Vivo Assessment of Rodent Plasmodium Parasitemia and Merozoite Invasion by Flow Cytometry
Published on: April 5, 2015
Blood Smear Image Based Malaria Parasite and Infected-Erythrocyte Detection and Segmentation
Meng-Hsiun Tsai1, Shyr-Shen Yu, Yung-Kuan Chan
1Department of Management Information Systems, National Chung Hsing University, Taichung City, Taiwan, Republic of China, mht@nchu.edu.tw.
Abstract:
In this study, an automatic malaria parasite detector is proposed to perceive the malaria-infected erythrocytes in a blood smear image and to separate parasites from the infected erythrocytes. The detector hence can verify whether a patient is infected with malaria. It could more objectively and efficiently help a doctor in diagnosing malaria. The experimental results show that the proposed method can provide impressive performance in segmenting the malaria-infected erythrocytes and the parasites from a blood smear image taken under a microscope. This paper also presents a weighted Sobel operation to compute the image gradient. The experimental results demonstrates that the weighted Sobel operation can provide more clear-cut and thinner object contours in object segmentation.
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