Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

114
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
114
Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

123
Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
123
Modified-Release Drug Delivery Systems: Rate-Programmed II01:19

Modified-Release Drug Delivery Systems: Rate-Programmed II

91
Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...
91

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A blood-brain barrier model based on flexible tubes to tailor the biophysical and chemical environment for drug delivery testing.

Materials today. Bio·2026
Same author

Nature's blueprint: Exopolysaccharides linking microbiome dynamics to advanced bone tissue engineering.

Carbohydrate polymers·2026
Same author

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Unraveling the potential and challenges of photosynthetic microalgae for oxygenating engineered tissues.

Biomaterials advances·2026
Same author

Superbase ionic liquid mediated solubilization of curcumin for improved bioavailability and anticancer efficacy.

Scientific reports·2026
Same author

Stable Protein-Based G-Quadruplex-Derived Supramolecular Bioinks as Tunable ECM-Mimetic Constructs Assembled by Combining Non-Covalent and Covalent Strategies.

Advanced materials (Deerfield Beach, Fla.)·2026

Related Experiment Video

Updated: Apr 5, 2026

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
11:13

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules

Published on: August 19, 2015

8.8K

Polysaccharide-Based Nanobiomaterials as Controlled Release Systems for Tissue Engineering Applications.

Eustolia Rodriguez-Velazquez1, Manuel Alatorre-Meda, Joao F Mano

  • 1Departamento de Estomatologia, Facultad de Odontologia, Instituto de Ortopedia y Banco de Tejidos Musculoesqueleticos, Grupo de Fisica de Coloides y Polimeros, Departamento de Fisica de Materia Condensada, Facultad de Fisica, Universidad de Santiago de Compostela, Campus Sur S/N, E-15782 Santiago de Compostela, Spain. eustolia.rodriguez@gmail.com.

Current Pharmaceutical Design
|August 21, 2015
PubMed
Summary

Polysaccharide-based nanomaterials show promise for tissue engineering and regenerative medicine (TERM). These biocompatible materials can be engineered into various nanoscale structures for effective drug delivery and biomimetic applications.

More Related Videos

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

9.2K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

9.2K

Related Experiment Videos

Last Updated: Apr 5, 2026

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
11:13

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules

Published on: August 19, 2015

8.8K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

9.2K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

9.2K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Regenerative Medicine

Background:

  • Polysaccharides are biocompatible biopolymers with high water absorption and modifiable properties.
  • They mimic the natural extracellular matrix (ECM) and can stabilize bioactive molecules for cellular applications.
  • Tissue Engineering and Regenerative Medicine (TERM) seeks to restore tissue function, often utilizing biomimetic approaches.

Purpose of the Study:

  • To review the current status of polysaccharide-based nanomaterials for drug delivery in TERM.
  • To explore how nanotechnology contributes to developing biomimetic systems for TERM.
  • To discuss various nanoscale configurations (0D, 1D, 2D, 3D) of these materials and their applications.

Main Methods:

  • Review of scientific literature on polysaccharide-based nanomaterials in TERM.
  • Analysis of different nanoscale architectures (nanoparticles, nanorods, nanofilms, nanofibrillar mats).
  • Discussion of applications in drug delivery and biomimicry for cellular manipulation.

Main Results:

  • Polysaccharides offer versatile platforms for creating nanoscale drug delivery systems.
  • Nanomaterials based on polysaccharides can effectively replicate natural ECM structures.
  • Various dimensional configurations (0D-3D) of polysaccharide nanomaterials are suitable for TERM applications.

Conclusions:

  • Polysaccharide-based nanomaterials are critical for advancing TERM and regenerative medicine.
  • Nanotechnology enables the development of sophisticated biomimetic systems using these materials.
  • Further research into polysaccharide nanomaterials holds significant potential for future therapeutic strategies.