Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.9K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.9K
Genetics of Speciation02:16

Genetics of Speciation

23.3K
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
23.3K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.3K
Frequency-dependent Selection01:21

Frequency-dependent Selection

24.5K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
24.5K
Genetic Variation01:25

Genetic Variation

1.6K
Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Missing comparability: When genomic selection faces field variability. A case study in soybeans.

The plant genome·2026
Same author

Yield Performance, Combining Ability and Stability of Early- to Medium-Maturing Doubled-Haploid Maize Lines in Eastern Africa.

Plant breeding = Zeitschrift fur Pflanzenzuchtung·2026
Same author

Performance of doubled haploid maize (Zea mays L.) testcross hybrids under optimal and drought-stressed environments.

PloS one·2026
Same author

Multimodal genomic prediction is not a buzzword: why modern plant breeding must integrate genomics, enviromics, and phenomics.

G3 (Bethesda, Md.)·2026
Same author

Introgression of QTL hotspot regions enhances grain yield and maize lethal necrosis resistance in elite maize lines.

Scientific reports·2026
Same author

Classification-based genomic prediction for early identification of high-yielding and stable soybean genotypes.

Frontiers in plant science·2026

Related Experiment Video

Updated: Apr 5, 2026

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

47.1K

A Genomic Selection Index Applied to Simulated and Real Data.

J Jesus Ceron-Rojas1, José Crossa2, Vivi N Arief3

  • 1Biometrics and Statistics Unit, International Maize and Wheat Improvement Center (CIMMYT), 06600, México Distrito Federal, México.

G3 (Bethesda, Md.)
|August 21, 2015
PubMed
Summary

Genomic selection index (GSI) theory was developed and validated using simulated and real data. Genomic selection index proved more efficient than phenotypic selection index over time.

Keywords:
GenPredgenomic estimated breeding valuegenomic selectionnet genetic meritselection indexselection responseshared data resource

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

8.1K
Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella
07:11

Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella

Published on: May 13, 2019

10.2K

Related Experiment Videos

Last Updated: Apr 5, 2026

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

47.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

8.1K
Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella
07:11

Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella

Published on: May 13, 2019

10.2K

Area of Science:

  • Animal breeding and genetics
  • Quantitative genetics
  • Genomic selection

Background:

  • Genomic selection index (GSI) theory has been proposed but lacks validation with empirical data.
  • Previous studies have not detailed methods for estimating GSI selection response or genetic gain for unobserved traits in subsequent cycles.
  • Accurate prediction of genetic merit and selection of parents are crucial in breeding programs.

Purpose of the Study:

  • To develop and validate the theory of a genomic selection index (GSI).
  • To compare the efficiency of GSI against the phenotypic selection index (PSI).
  • To establish methods for estimating selection response and genetic gain for observed and unobserved traits using GSI.

Main Methods:

  • Developed GSI theory and applied it to simulated and real datasets across four traits.
  • Numerically compared GSI efficiency with PSI using response ratios and expected genetic gain per cycle.
  • Utilized Technow inequality for a comparative efficiency analysis between GSI and PSI.

Main Results:

  • GSI theory was successfully applied to both simulated and real data, confirming theoretical predictions.
  • GSI demonstrated higher efficiency compared to PSI on a per-unit-of-time basis.
  • The study provided a framework for estimating genetic gains in subsequent selection cycles for both observed and unobserved traits.

Conclusions:

  • The developed GSI is a validated and efficient tool for predicting genetic merit and selecting parents.
  • GSI offers a more time-efficient approach to achieving genetic gains compared to PSI.
  • The methodology allows for the estimation of genetic progress in unobserved traits, enhancing breeding program predictability.