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Disseminated Herpes Simplex Virus with Fulminant Hepatitis
Bassam H Rimawi1, Joseph Meserve2, Ramzy H Rimawi3
1Division of Maternal Fetal Medicine and Reproductive Infectious Diseases, Department of Gynecology and Obstetrics, Emory University School of Medicine, 550 Peachtree Street, 8th Floor, Atlanta, GA 30303, USA.
Abstract:
Disseminated herpes simplex virus (HSV) is a rare cause of acute fulminant liver failure. We hereby present a case series of three patients with acute disseminated HSV with necrotizing hepatitis successfully treated with a week course of acyclovir. Early empiric administration of acyclovir therapy while awaiting confirmatory tests is critical in this potentially lethal disease.
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