Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

3.7K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
3.7K
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

792
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
792
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

1.4K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.4K
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

1.8K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
1.8K
Abdominal Regions and Quadrants01:19

Abdominal Regions and Quadrants

19.6K
To promote clear communication, for instance, about the location of a patient's abdominal pain or a suspicious mass, anatomists and clinicians typically use imaginary lines to categorize the abdominopelvic cavity into either four quadrants or nine regions to identify organs in the cavity.
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four...
19.6K
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

611
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
611

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Musashi1 Enhances Cell Growth and Increases Chemoresistance in Neuroblastoma.

Anticancer research·2026
Same author

Tradition and Transformation: The Legacy of the Southern Surgical Association in Changing Times.

Journal of the American College of Surgeons·2026
Same author

Carcinoma sequence inferred from increasing age at choledochal cyst excision.

Surgery·2025
Same author

Perioperative Blood Transfusion and Infectious Complications Among Pediatric Patients with Cancer.

Children (Basel, Switzerland)·2025
Same author

Tissue-dependent mechanosensing by cells derived from human tumors.

bioRxiv : the preprint server for biology·2025
Same author

Caught in the Crossfire: 10-Year Experience with Pediatric Firearm Injury at a Single Institution.

Journal of the American College of Surgeons·2025

Related Experiment Video

Updated: Apr 5, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

10.9K

Non-fecalith-induced appendicitis: etiology, imaging, and pathology.

Leonard E Swischuk1, Dai H Chung2, Hal K Hawkins3

  • 1Department of Radiology and Pediatrics, The University of Texas Medical Branch, Galveston, TX, USA. lswischu@utmb.edu.

Emergency Radiology
|August 22, 2015
PubMed
Summary

Non-fecalith-induced appendicitis often presents with lymphoid hyperplasia, particularly in younger patients. This finding challenges the traditional view that fecaliths are the primary cause of appendicitis.

Keywords:
AppendicitisImagingLymphoid hyperplasia

More Related Videos

PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models
04:05

PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models

Published on: June 6, 2025

466
Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.4K

Related Experiment Videos

Last Updated: Apr 5, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

10.9K
PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models
04:05

PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models

Published on: June 6, 2025

466
Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.4K

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Pathology

Background:

  • Appendicitis is a common surgical emergency, typically associated with fecalith obstruction.
  • Non-fecalith causes, such as lymphoid hyperplasia, are less understood.
  • Differentiating appendicitis causes is crucial for accurate diagnosis and treatment.

Purpose of the Study:

  • To document imaging and pathology findings in non-fecalith-induced appendicitis.
  • To investigate the role of lymphoid hyperplasia as a cause of appendicitis.
  • To compare appendicitis with and without fecalith involvement.

Main Methods:

  • Retrospective review of imaging and pathology in 40 patients with purulent appendicitis.
  • Classification of appendicitis based on appendiceal involvement (total vs. tip).
  • Correlation of findings with fecalith presence and lymphoid hyperplasia.

Main Results:

  • 55% of appendicitis cases had a fecalith; 45% did not.
  • Appendicitis involving predominantly the appendix tip showed marked lymphoid hyperplasia in 100% of cases.
  • Lymphoid hyperplasia was identified as the underlying cause in 45% of cases, suggesting it as a significant predisposing factor.

Conclusions:

  • Lymphoid hyperplasia is a significant cause of non-fecalith-induced appendicitis, especially in younger individuals.
  • Findings suggest a shift in understanding appendicitis etiology, highlighting hyperplasia as a key factor.
  • Further research is warranted to explore the mechanisms and diagnostic implications of lymphoid hyperplasia in appendicitis.