[Magnesium in the cerebrospinal fluid of patients with chronic uremia]

The levels of magnesium were determined in the cerebrospinal fluid if healthy subjects and patients with uraemia. The effect of plasma alkalization with sodium bicarbonate on possible changes of magnesium concentration in the CSF was studied. It was found that in healthy subjects magnesium concentration of the CSF was higher than in plasma, and was increased further in chronic uraemia. Plasma alkalization in uraemia with sodium bicarbonate reduced the concentration of magnesium in the CSF.