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[HLA antigen frequencies in patients with autosomal dominant polycystic kidney degeneration]
J Spengler1, S Wegener, H Schüler
1Klinik und Poliklinik für Innere Medizin, Bereiches Medizin, Ernst-Mortiz-Arndt-Universität Greifswald.
Abstract:
20 non-related patients suffering from autosomal dominantly polycystic renal disease were HLA-A, -B, -C and -DR typified and the HLA frequencies were compared with the normal population. Tissue typing was performed using the lymphocytotoxicity test using 180 well-characterized test sera. In contrast to the literature no significant differences were found. However, the value of erythrocytic phosphoglycolate-phosphatase-phenotyping should be checked in the genetic control and consultation.