Histopathologic Finding of Both Gastric and Respiratory Epithelia in a Lingual Foregut Cyst

Area of Science:

• Pediatric Surgery
• Developmental Biology
• Gastroenterology

Background:

• Foregut cysts are uncommon congenital lesions found along the gastrointestinal or respiratory tracts.
• Oral cavity foregut cysts, particularly those on the tongue, are exceptionally rare.
• These lesions can cause feeding or respiratory issues in infants.

Purpose of the Study:

• To report an extremely rare case of a foregut cyst involving the floor of the mouth and anterior tongue in an infant.
• To highlight the unique histological finding of dual gastric and respiratory epithelia within a single oral cyst.
• To emphasize the importance of considering foregut cysts in the differential diagnosis of pediatric oral lesions.

Main Methods:

• Case presentation of a 4-month-old female infant with a congenital oral lesion.
• Clinical examination and imaging (details not specified in abstract).
• Surgical excision and detailed histopathological analysis of the cyst.

Main Results:

• A foregut cyst was identified in the floor of the mouth and anterior tongue.
• Histological examination revealed the cyst was lined by both gastric and respiratory epithelia.
• This dual epithelial lining within a single tongue cyst is an extremely rare finding.

Conclusions:

• Foregut cysts, though rare, should be considered in the differential diagnosis of floor of mouth and tongue lesions in infants.
• The presence of both gastric and respiratory epithelia in a single oral foregut cyst is exceptionally uncommon.
• This case underscores the diverse presentations and histological variations of congenital foregut-derived lesions.