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[Anesthesiologic tactics in the case of children with rheumatoid arthritis receiving hormonal therapy]
Anesteziologiia I Reanimatologiia
|November 1, 1989
Insights
This study compared two perioperative corticosteroid therapies in children with rheumatoid arthritis. Small doses and tailored application of steroid hormones effectively prevent side effects and improve surgical outcomes.
Area of Science:
- Pediatric Rheumatology
- Endocrinology
- Anesthesiology
Context:
- Rheumatoid arthritis (RA) management in children requires careful consideration of perioperative care.
- Corticosteroid therapy is common in pediatric RA but carries risks, especially around surgery.
- Optimizing steroid regimens is crucial for minimizing complications in pediatric surgical patients.
Purpose:
- To compare the efficacy of two perioperative corticosteroid therapy regimens in children with rheumatoid arthritis.
- To evaluate the effectiveness of low-dose steroid hormone use for preventing acute adrenocortical insufficiency.
- To determine if a differential approach to glucocorticoid application can mitigate side effects.
Summary:
- A study involving 191 children (aged 4-15) with rheumatoid arthritis compared two perioperative corticosteroid therapies.
- Patients received preoperative steroid hormone treatment.
- Findings indicate that low-dose steroid hormone use for preventing acute adrenocortical insufficiency, combined with a tailored application strategy, effectively minimizes glucocorticoid side effects.
Impact:
- This research suggests a safer and more favorable perioperative management strategy for children with rheumatoid arthritis undergoing surgery.
- The findings support the use of optimized corticosteroid regimens to reduce adverse events in pediatric surgical patients.
- Implementing these findings can lead to improved surgical outcomes and patient recovery in pediatric rheumatology.
Abstract:
The efficacy of two types of perioperative corticosteroid therapy has been compared in 191 children with rheumatoid arthritis aged 4 to 15 years, who were preoperatively treated with steroid hormones. The data have been obtained that small doses of steroid hormones used for the prevention of acute adrenocortical insufficiency and differential approach to their application eliminate side effects of glucocorticoids and ensure more favourable conditions for surgery.
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