Related Experiment Video
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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
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Fatal intracerebral bleeding under rivaroxaban
Claudia Stöllberger1, Adam Bastovansky1, Josef Finsterer1
1Krankenanstalt Rudolfstiftung, Juchgasse 25, A-1030 Wien, Austria.
International Journal of Cardiology
|August 22, 2015
Summary
Rivaroxaban, a factor Xa inhibitor, may not offer the same intracranial hemorrhage safety outside clinical trials. Close patient monitoring for rivaroxaban is crucial, especially with interacting drugs and comorbidities.
Area of Science:
- Pharmacology
- Cardiology
- Neurology
Background:
- Rivaroxaban, a direct factor Xa inhibitor, is non-inferior to warfarin for atrial fibrillation.
- Clinical trials suggest lower intracranial hemorrhage rates with rivaroxaban compared to vitamin K antagonists (VKAs).
- Real-world data on rivaroxaban's intracranial hemorrhage risk outside controlled trials are limited.
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