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Published on: February 14, 2017
[Clinical and electrocardiographic aspects of mitral valve prolapse]
Insights
This study compared cardiac arrhythmias in patients with mitral valve prolapse (MVP) and healthy controls. Patients with MVP showed a higher prevalence of tachyarrhythmias on EKG, suggesting a potential link between MVP and cardiac electrical instability.
Area of Science:
- Cardiology
- Electrophysiology
- Valvular Heart Disease
Context:
- Mitral valve prolapse (MVP) is a common valvular heart condition.
- Cardiac arrhythmias can occur in patients with MVP, but their prevalence and characteristics require further investigation.
- Electrocardiogram (EKG) is a primary tool for diagnosing cardiac arrhythmias.
Purpose:
- To analyze and compare the occurrence of cardiac arrhythmias in patients diagnosed with mitral valve prolapse (MVP) versus a control group with normal echocardiograms.
- To investigate potential differences in EKG abnormalities, including ST segment, T wave, QT interval, and PR interval, between the two groups.
- To assess the prevalence of tachyarrhythmias and ventricular premature depolarizations in patients with and without MVP.
Summary:
- A study involving 126 cardiology outpatients (63 with MVP, 63 controls) revealed that women constituted a higher proportion in both groups.
- While palpitations, chest pain, and dyspnea were common symptoms in both groups, patients with MVP exhibited a higher incidence of tachyarrhythmias (31.5% vs. 16.5%) and ventricular premature depolarizations (22% vs. 13.5%) on EKG.
- No significant differences were observed in ST and T wave abnormalities, corrected QT interval prolongation, or PR intervals between the MVP and control groups.
Impact:
- The findings suggest a potential association between mitral valve prolapse and an increased risk of tachyarrhythmias.
- This research highlights the importance of EKG monitoring in patients with MVP to detect potential electrical abnormalities.
- Further investigation is warranted to elucidate the mechanisms linking MVP to cardiac arrhythmias and to inform clinical management strategies.
Abstract:
Group sex and age, symptoms, ST segment, T wave, QT interval and PR interval abnormalities on the EKG, as whereas cardiac arrhythmias were analysed in two groups of patients from the cardiology outpatient clinics: patients from group I (n = 63) had and echocardiographic diagnosis of mitral valve prolapse (MVP), whereas patients from group II (n = 63) had a normal echocardiogram. Women exceeded men in number in both groups, and the female/male ratio was 2.5:1 and 1.5:1 in groups I and II, respectively. The age range in group I was 54 years (15-69) with a mean of 29.3 +/- 10.8 years, whereas group II had an age range of 49 years (9-58) and a mean of 26.5 +/- 10.1 years. Palpitations, atypical precordial pain and dyspnea were the most frequent presenting symptoms in both groups, all been present in 52 (88.2%) of the patients from group I and in 45 (71.5%) from group II. ST and T abnormalities occurred in 2 (4%) patients from group I and in 8 (13%) from group II. The PR interval was equal to or shorter than 0.20s in all cases. The corrected QT interval (Q-Tc) was prolonged in 2 (4%) patients from group I and in 1 (1.5%) from group II. The tachyarrhythmias as a whole, when analysed through the conventional 12-lead EKG, were found in 17 (31.5%) of the group I patients and in 10 (16.5%) of the patients from group II. Ventricular premature depolarizations were detected in 12 (22%) patients from group I and in 8 (13.5%) from group II (p greater than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
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