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Updated: Apr 5, 2026

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
Published on: October 1, 2016
A highly selective and sensitive fluorescent sensor for the rapid detection of Hg²⁺ based on
Qingfen Niu1, Xingxing Wu1, Shanshan Zhang1
1Shandong Provincial Key Laboratory of Fine Chemicals, Qilu University of Technology, Jinan 250353, People's Republic of China.
Abstract:
A fast-responsive fluorescent phenylamine-oligothiophene sensor 3TDDA was reported. This sensor exhibited highly selective and sensitive detection of Hg(2+) ion in aqueous solution (THF/CH3CN/H2O, 45/50/5, v/v) through fluorescence quenching. The detection was not affected by the coexistence of other competitive metal ions such as Na(+), K(+), Ag(+), Ca(2+), Fe(3+), Al(3+), Co(2+), Ni(2+), Zn(2+), Pb(2+), Cd(2+), Fe(2+) and Cr(3+). A stoichiometric ratio (1:1) of the sensor and Hg(2+) was determined by a Job's plot and mole-ratio curves. The binding of sensor 3TDDA and Hg(2+) was also chemically reversible with EDTA. The detection limit was calculated as low as 4.392×10(-7) M.

