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Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Vaccines01:21

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Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
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Cancer Vaccines01:30

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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[DNA Double-Strand Break Repair System by a Mechanism of Non-Homologous End Joining Provides Resistance to DNA-Damaging and Oxidizing Stresses in the Yeast Debaryomyces hansenii].

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Related Experiment Video

Updated: Apr 5, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
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Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

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[Rabies vaccines: Current status and prospects for development].

E S Starodubova1,2, O V Preobrazhenskaia1, Y V Kuzmenko1

  • 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.

Molekuliarnaia Biologiia
|August 25, 2015
PubMed
Summary

Rabies prevention relies on prompt treatment, including vaccination and immunoglobulin. Modern rabies vaccine development focuses on new technologies like recombinant viruses and DNA vaccines for improved safety and efficacy.

Keywords:
glycoproteinrabiesrabies vaccine

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Area of Science:

  • Virology
  • Immunology
  • Biotechnology

Context:

  • Rabies is a fatal zoonotic viral disease with no cure, necessitating effective prevention strategies.
  • Vaccination and post-exposure prophylaxis are critical for rabies prevention.
  • Historical development of rabies vaccines spans over a century.

Purpose:

  • To review modern trends in the development of rabies vaccines.
  • To highlight advancements in vaccine production technologies.
  • To discuss new-generation rabies vaccine candidates.

Summary:

  • Current rabies vaccine development utilizes molecular biology and biotechnology for safer and more effective production.
  • New approaches include recombinant rabies virus strains and production of the rabies virus glycoprotein (G protein).
  • Emerging vaccine platforms involve nonpathogenic viruses, plant-based systems, and DNA vaccines.

Impact:

  • Advances in rabies vaccine technology promise enhanced safety and efficacy.
  • Development of novel vaccines could improve global rabies control efforts.
  • New vaccine strategies may offer alternative and improved methods for rabies prevention.