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Updated: Apr 5, 2026

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CIRCLE-Seq for Interrogation of Off-Target Gene Editing
Published on: November 1, 2024
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Abstract:
Ethical questions in medicine tend to emphasize the intentions of researchers and physicians. Questions concerning harm have more often been addressed in terms of legal culpability. This commentary proposes that normalizing interventions for atypical sex anatomies, both historical and ongoing, be recognized as a kind of medical error, and that attention be focused not simply on prevention, but on repair.
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