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Hypertension in the African American population: A succinct look at its epidemiology, pathogenesis, and therapy

Luis M Ortega1, Emad Sedki1, Ali Nayer2

  • 1Division of Nephrology and Hypertension. Allegheny General Hospital/Temple University School of Medicine. Pittsburgh, Pennsylvania (Estados Unidos).

Nefrologia : Publicacion Oficial De La Sociedad Espanola Nefrologia
|August 25, 2015
PubMed

Insights

Arterial hypertension is common in Black Americans, causing significant cardiovascular and kidney damage. Effective treatment requires lifestyle changes and antihypertensive medication, though the best drug choice remains undetermined.

Area of Science:

  • Cardiology
  • Nephrology
  • Public Health

Background:

  • Arterial hypertension disproportionately affects the Black population in the United States.
  • Hypertension is a major risk factor for cardiovascular disease and kidney damage.
  • Complex pathogenesis involves obesity, salt sensitivity, and renin-angiotensin-aldosterone system activation.

Purpose of the Study:

  • To review the challenges and recommendations for managing arterial hypertension in Black Americans.
  • To highlight the need for tailored therapeutic strategies.

Main Methods:

  • Literature review of existing studies and guidelines on hypertension in Black populations.
  • Analysis of contributing factors to hypertension pathogenesis.
  • Evaluation of current treatment recommendations.

Main Results:

  • The International Society of Hypertension in Blacks recommends dietary intervention for systolic/diastolic blood pressure >115/75 mmHg.
  • Target blood pressure should be maintained below 135/85 mmHg with appropriate antihypertensive medication.
  • The optimal antihypertensive drug for this demographic is not yet established.

Conclusions:

  • Management of arterial hypertension in Black Americans requires a multifaceted approach.
  • Combined dietary interventions and antihypertensive pharmacotherapy are essential.
  • Further research is needed to determine the most effective antihypertensive agents for this population.

Keywords:
African AmericanAfroamericanosAmericansAntihipertensivosAntihypertensives for AfricanEpidemiology of hypertensionEpidemiología de la hipertensiónHipertensiónHypertensionPathogenesis of hypertensionPatogénesis de la hipertensiónpara afroamericanos

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