Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

86.5K
Overview
86.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune hyperactivity in hemodialysis patients is associated with interferon gamma-induced trained immunity.

iScience·2026
Same author

Myeloid-avid mammalian target of rapamycin-inhibiting nanobiologic attenuates allograft fibrosis after lung transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2026
Same author

Effect of PI3K-p110α Inhibitor Alpelisib in the Differentiation and Effector Functions of M-CSF and GM-CSF Macrophages.

International journal of molecular sciences·2026
Same author

Transcriptional and Epigenetic Plasticity Drive an Alternative Non-clonal Mechanism of Resistance to <i>Kras</i> <sup>G12D</sup> Inhibition in Pancreatic Cancer.

Cancer communications (London, England)·2026
Same author

c-FLIP as a master regulator of immune homeostasis and disease mechanisms.

Cell death & disease·2026
Same author

The sialic shield of leukemia cells.

Science (New York, N.Y.)·2026

Related Experiment Video

Updated: Apr 5, 2026

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
18:48

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

Published on: August 12, 2017

15.0K

Monocyte-Derived Suppressor Cells in Transplantation.

Jordi Ochando1, Patricia Conde1, Vincenzo Bronte2

  • 1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.

Current Transplantation Reports
|August 25, 2015
PubMed
Summary

Myeloid-derived suppressor cells (MDSC) are immune cells that regulate immune responses. This review focuses on monocytic-derived suppressor cells in solid organ transplantation.

Keywords:
Immune regulationMDSCSuppressor MCsTransplantation

More Related Videos

Functional Characterization of Regulatory Macrophages That Inhibit Graft-reactive Immunity
08:41

Functional Characterization of Regulatory Macrophages That Inhibit Graft-reactive Immunity

Published on: June 7, 2017

8.7K
Preparation of Myeloid Derived Suppressor Cells MDSC from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting AutoMACS
14:15

Preparation of Myeloid Derived Suppressor Cells MDSC from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting AutoMACS

Published on: June 18, 2012

27.0K

Related Experiment Videos

Last Updated: Apr 5, 2026

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
18:48

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

Published on: August 12, 2017

15.0K
Functional Characterization of Regulatory Macrophages That Inhibit Graft-reactive Immunity
08:41

Functional Characterization of Regulatory Macrophages That Inhibit Graft-reactive Immunity

Published on: June 7, 2017

8.7K
Preparation of Myeloid Derived Suppressor Cells MDSC from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting AutoMACS
14:15

Preparation of Myeloid Derived Suppressor Cells MDSC from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting AutoMACS

Published on: June 18, 2012

27.0K

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • Myeloid-derived suppressor cells (MDSC) are key negative regulators of immune responses.
  • MDSC are a heterogeneous population including monocytic (M-MDSC) and granulocytic (G-MDSC) subtypes.
  • Recent nomenclature suggests 'suppressive monocyte derived cells' (suppressive MCs) for specific mouse suppressor cells.

Approach:

  • This work is a literature review.
  • The review focuses on monocytic-derived cells with suppressor functions.
  • The context is solid organ transplantation.

Key Points:

  • Monocytic-derived cells exhibit potent in vitro and in vivo suppressor functions.
  • Understanding these cells is crucial for managing immune responses post-transplantation.
  • The nomenclature for these cells is evolving.

Conclusions:

  • Monocytic-derived suppressor cells play a significant role in immune regulation within solid organ transplantation.
  • Further research into suppressive MCs may offer therapeutic targets.
  • Clarifying the terminology and function of these cells is essential for the field.