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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Primary Lymphoid Organs01:16

Primary Lymphoid Organs

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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
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Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Related Experiment Video

Updated: Apr 5, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

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T-lymphoblastic lymphoma with cutaneous involvement.

Emmanuelle Ginoux1, Fanny Julia1, Brigitte Balme1

  • 1Emmanuelle Ginoux, Fanny Julia, Luc Thomas, Stéphane Dalle, Department of Dermatology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69002 Lyon, France.

World Journal of Clinical Cases
|August 25, 2015
PubMed
Summary

T-lymphoblastic lymphoma (T-LBL) can manifest as skin lesions, aiding early diagnosis. This aggressive cancer requires specialized pathology and treatment, including potential bone-marrow transplantation, for better patient outcomes.

Area of Science:

  • Oncology
  • Dermatology
  • Hematopathology

Background:

  • T-lymphoblastic lymphoma (T-LBL) is an aggressive hematologic malignancy.
Keywords:
Cutaneous lymphomaLymphoblastic lymphomaSkin

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  • Cutaneous involvement in T-LBL can present as a diagnostic challenge.
  • Early recognition of dermatological signs is crucial for timely diagnosis and management.