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Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
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Genetic association analyses highlight biological pathways underlying mitral valve prolapse

Christian Dina1,2, Nabila Bouatia-Naji3,4, Nathan Tucker5

  • 1INSERM Unité Mixte de Recherche (UMR) 1087, Centre National de la Recherche Scientifique (CNRS) UMR 6291, Institut du Thorax, Nantes, France.

Nature Genetics
|August 25, 2015
PubMed
Summary

This study identified the first genetic risk loci for nonsyndromic mitral valve prolapse (MVP), a common heart valve condition. Findings suggest new mechanisms contributing to mitral regurgitation, a primary cause of valve repair.

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