Lower respiratory tract disorder hospitalizations among children born via elective early-term delivery
Insights
Elective early-term delivery is linked to a higher risk of childhood lower respiratory tract disorder hospitalizations. This finding supports discouraging non-medically indicated early-term inductions to protect infant respiratory health.
Area of Science:
- Obstetrics and Gynecology
- Pediatrics
- Public Health
Background:
- Elective early-term delivery is common, but its long-term effects on infant health are not fully understood.
- Lower respiratory tract disorders are a significant cause of childhood morbidity.
Purpose of the Study:
- To investigate the association between elective early-term delivery and the risk of hospitalization for lower respiratory tract disorders in children.
- To examine specific respiratory conditions, including asthma, bronchiolitis, bronchitis, and pneumonia.
Main Methods:
- Retrospective cohort study using Washington State birth certificate and hospital discharge data.
- Comparison of children born via early-term elective induction versus full- or late-term elective induction.
- Analysis of hospitalization odds before age five and cause-specific odds ratios, with subgroup analysis excluding perinatal complications.
Main Results:
- Electively induced early-term children had a significantly increased risk of hospitalization for lower respiratory disorders before age five (adjusted OR: 1.31).
- Bronchiolitis showed a statistically significant increase in hospitalization odds.
- Comparable, though not always statistically significant, increases were observed for asthma and pneumonia.
Conclusions:
- An association exists between electively induced early-term delivery and increased hospitalization for lower respiratory tract disorders in early childhood.
- Findings support current policies that discourage elective early-term delivery.
- Further research may explore underlying mechanisms linking early-term birth and respiratory issues.
Objective:
We evaluated the hypothesis that elective early-term delivery increases the risk of childhood lower respiratory tract disorder hospitalization.
Methods:
Children born via early-term elective inductions were compared to full- or late-term elective inductions in a retrospective cohort study using Washington State birth certificate and hospital discharge data. Outcomes were the odds of lower respiratory disorder hospitalization before age five and cause specific odds ratios for asthma, bronchiolitis, bronchitis, and pneumonia. In addition, a subgroup analysis excluding infants with perinatal complications was conducted.
Results:
Electively induced early-term children were at significantly increased risk of hospitalization before age five for lower respiratory disorders compared to similar full- or late-term children (adjusted OR: 1.31, 95% CI: 1.11-1.55). Bronchiolitis was the only cause-specific outcome with a statistically significant increase in odds of hospitalization, though comparable increases were found for the less common diagnoses of asthma (adjusted OR: 1.39, 95% CI: 0.93-2.08) and pneumonia (adjusted OR: 1.27, 95% CI: 0.99-1.64). Excluding infants with perinatal complications did not alter the results.
Conclusions:
There was an association between electively induced early-term delivery and hospitalization for lower respiratory tract disorders before age five. This reinforces policies discouraging elective early-term delivery.
More Related Videos
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
04:21A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
Published on: August 4, 2021
Related Concept Videos
Common Respiratory Disorders
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Pulmonary Cycle: Exhalation
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Microbiota of the Respiratory Tract
Other Pulmonary Disorders
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
