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Performance Evaluation of Three URiSCAN Devices for Routine Urinalysis
Kiwoong Ko1, Min-Jung Kwon1, Seungho Ryu2
1Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Journal of Clinical Laboratory Analysis
|August 26, 2015
Summary
URiSCAN devices demonstrate reliable diagnostic performance in routine urinalysis, showing good correlation with Roche analyzers, quantitative assays, and manual microscopy for most tests.
Area of Science:
- Clinical Chemistry
- Urinalysis Diagnostics
Background:
- Routine urinalysis is crucial for diagnosing various medical conditions.
- Automated urinalysis devices aim to improve efficiency and accuracy over manual methods.
Purpose of the Study:
- To compare the diagnostic performance of three URiSCAN devices against three Roche analyzers.
- To evaluate URiSCAN devices against manual microscopy and quantitative assays for key urinalysis parameters.
Main Methods:
- Eight dipstick tests were analyzed using three URiSCAN devices and three Roche analyzers.
- Leukocyte and erythrocyte results were compared to manual microscopy.
- Protein, glucose, pH, and specific gravity (SG) assays were compared to quantitative assays.
Main Results:
- Agreement rates within one grade difference exceeded 94.3% for most comparisons.
- URiSCAN devices showed good correlation with Roche analyzers and quantitative assays, except for SG.
- Diagnostic performance varied between specific URiSCAN and Roche models for leukocyte and erythrocyte detection.
Conclusions:
- URiSCAN devices exhibit well-correlated results with Roche analyzers, quantitative assays, and manual microscopy.
- The URiSCAN series is suitable for routine urinalysis in clinical laboratory settings.
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