[Anti-nDNA antibodies in lupus erythematosus]

Using the ELISA technique we have tested anti-nDNA antibodies in 79 patients affected with Lupus Erythematosus. The same patients have previously been tested for anti-cardiolipin antibodies. According to the literature, cross inhibition ELISA tests show no cross reactions between these two auto-antibodies families. Patients with highest anti-nDNA antibodies show a production of polyclonal (IgG, IgM, IgA) antinuclear antibodies responsible for a homogeneous pattern detected by indirect immunofluorescence.