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Updated: Apr 5, 2026

Ultrasonographic Assessment During Cardiopulmonary Resuscitation
Published on: October 24, 2020
Evaluation of Zoll Medical's ResQCPR System for cardiopulmonary resuscitation
Guillaume Debaty1, Anja Metzger, Keith Lurie
1a 1 University Grenoble Alps /CNRS/CHU de Grenoble/TIMC-IMAG UMR 5525, Grenoble, France.
Insights
The ResQCPR System significantly improves survival rates for cardiac arrest patients. This CPR adjunct increases the likelihood of survival with favorable neurological function after out-of-hospital cardiac arrest.
Area of Science:
- Emergency Medicine
- Cardiovascular Research
- Medical Devices
Background:
- Out-of-hospital cardiac arrest (OHCA) is a critical medical emergency with low survival rates.
- Current standard care involves standard cardiopulmonary resuscitation (S-CPR), yielding survival with favorable neurological function in less than 6% of patients.
- There is a need for advanced interventions to improve circulatory support during CPR.
Purpose of the Study:
- To evaluate the efficacy of the ResQCPR System as a CPR adjunct in patients with OHCA.
- To compare the survival outcomes of the ResQCPR System against conventional CPR (S-CPR).
- To assess the impact on survival with favorable neurological function.
Main Methods:
- A Phase III, multicenter randomized study was conducted.
- Adult patients experiencing OHCA of presumed cardiac etiology were enrolled.
- Participants were randomized to receive either the ResQCPR System or conventional CPR (S-CPR).
Main Results:
- The ResQCPR System demonstrated a 50% increase in survival to hospital discharge.
- This improvement was observed specifically in patients achieving favorable neurological function.
- The study compared outcomes against conventional CPR in OHCA patients.
Conclusions:
- The ResQCPR System is an effective CPR adjunct for improving survival in OHCA patients.
- The device enhances circulation to the heart and brain, increasing the likelihood of positive outcomes.
- FDA approval supports the use of the ResQCPR System for non-traumatic cardiac arrest in adults.
Abstract:
Cardiac arrest remains a leading cause of death, currently affecting more than 250,000 Americans annually. As recommended by the American Heart Association, the current standard of care for patients with an out-of-hospital cardiac arrest (OHCA) includes manual cardiopulmonary resuscitation (S-CPR). Survival with favorable neurological function for all patients following OHCA and treated with S-CPR averages <6%. The ResQCPR System is intended to provide greater circulation to the heart and brain compared with S-CPR, thereby increasing the likelihood of survival. A recent Phase III, multicenter randomized study demonstrated a 50% increase in survival to hospital discharge with favorable neurologic function in subjects with an OHCA of presumed cardiac etiology treated with the ResQCPR System compared with conventional CPR. The ResQCPR System has been recently approved by the FDA as a CPR adjunct to improve the likelihood of survival in adult patients with non-traumatic cardiac arrest.
Related Concept Videos
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation III: AED Use
Cardiopulmonary Resuscitation II: ACLS Airway Management
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

