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Updated: Apr 5, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
The Life Course Perspective: a Guide for Genetic Counselors
Rebekah J Hamilton1, Nancy A Innella2, Dawn T Bounds2
1Department of Women, Children & Family Nursing, Rush University College of Nursing, 2624 Newcastle Dr., Carrollton, TX, 75007, USA. rebekah_hamilton@rush.edu.
The life course perspective (LCP) offers genetic counselors a comprehensive framework for understanding individuals with genetic mutations. LCP examines temporal and contextual factors beyond immediate reactions to genetic test results.
Area of Science:
- Genetics
- Psychology
- Sociology
Background:
- Genetic counseling often focuses on immediate reactions to test results.
- Existing theories like PMT and CSMSR have limitations in capturing the full experience.
- The life course perspective (LCP) offers a broader temporal and contextual lens.
Purpose of the Study:
- To introduce the life course perspective (LCP) as a valuable tool in genetic counseling.
- To explore how LCP can enhance the understanding of individuals with genetic mutations.
- To demonstrate the application of LCP in the context of positive genetic test results, such as BRCA mutations.
Main Methods:
- Review of existing research utilizing the life course perspective (LCP).
- Analysis of LCP's application in diverse health-related studies (e.g., Alzheimer's, cancer).
- Conceptual integration of LCP into genetic counseling practice.
Main Results:
- LCP has been successfully applied in various health and social science research areas.
- LCP provides a framework to examine long-term and contextual influences on health experiences.
- Previous research demonstrates LCP's utility in understanding caregiver experiences and health disparities.
Conclusions:
- The life course perspective (LCP) is a robust theoretical framework for genetic counseling.
- Integrating LCP allows for a more comprehensive exploration of the lived experiences of individuals with genetic mutations.
- LCP can inform more holistic and personalized genetic counseling interventions.
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