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Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

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Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Related Experiment Video

Updated: Apr 5, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
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Striving to make births safer.

Daniel Allen

    Nursing Management (Harrow, London, England : 1994)
    |August 27, 2015
    PubMed
    Summary

    The Traffina Foundation for Community Health (TFCH) works to decrease maternal and infant mortality in Nigeria. This non-profit addresses complications from pregnancy and childbirth.

    Area of Science:

    • Public Health
    • Global Health
    • Maternal Health

    Background:

    • High rates of maternal and infant mortality persist in Nigeria due to complications during pregnancy and delivery.
    • The Traffina Foundation for Community Health (TFCH) was established to address this critical public health issue.

    Purpose of the Study:

    • To highlight the work of the TFCH in reducing maternal and infant deaths in Nigeria.
    • To underscore the importance of non-profit organizations in improving maternal healthcare outcomes.

    Main Methods:

    • The TFCH operates as a non-profit organization.
    • Focuses on community health initiatives to mitigate pregnancy and delivery complications.

    Main Results:

    • TFCH has been active for eight years, contributing to the reduction of preventable deaths.

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  • Nurse leader Chinomnso Ibe founded the organization to tackle maternal health challenges.
  • Conclusions:

    • Non-profit interventions are crucial for improving maternal health in resource-limited settings.
    • Continued support for organizations like TFCH is vital for sustainable reductions in maternal mortality.