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Updated: Apr 5, 2026

Isolation and Expansion of Cytotoxic Cytokine-induced Killer T Cells for Cancer Treatment
Published on: January 24, 2020
Cytokine-induced killer cells as immunotherapy for solid tumors: current evidence and perspectives
Lidia Giraudo1,2, Loretta Gammaitoni2, Michela Cangemi2
1Department of Oncology, University of Torino, Turin, Italy.
Abstract:
Cytokine-induced killer (CIK) cells are ex vivo expanded T lymphocytes endowed with potent MHC-independent antitumor activity. CIK cells are emerging as promising therapeutic approach in the field of cancer adoptive immunotherapy, with biologic features favoring their transferability into clinical applications. Aim of this review is to present the biologic characteristic of CIK cells, discussing the main preclinical findings and initial clinical applications in the field of solid tumors.
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