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Published on: February 12, 2018
[Clinical study of anti-Mullerian hormone in prediction of ovarian aging]
Lihong Gao1, Wenwei Cai, Qin Zhu
1Department of Obstetrics and Gynecology, Jiaxing Maternity and Child Health Care Hospital, Jiaxing 314000, China.
Objective:
To explore the serum anti-Mullerian hormone (AMH) level in women of childbearing age with normal menstrual cycles.
Methods:
A total of 1 423 women with regular menstrual cycles were selected and divided into 5 groups according to their ages, i.e. ≤ 25, 26-30, 31-35, 36-40, ≥ 41 years. Their serum levels of AMH were measured, and the relationship between AMH and age was analyzed.
Results:
The serum AMH levels of 5 groups according to ages (≤ 25, 26-30, 31-35, 36-40, ≥ 41 years) were 3.62, 3.10, 2.27, 1.07, 0.45 µg/L, respectively. The comparison of serum AMH levels in different age groups had significant difference (P < 0.01). Serum AMH level declined with increasing age, and dropped significantly after 36. The serum AMH level and age showed a negative correlation with significant difference (r = -0.374, P < 0.01). Quadratic regression of logAMH proximally reflected the relationship between AMH and age.
Conclusion:
AMH determination for women of childbearing age could provide reference for the evaluation of ovarian function.
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