[Disruption of biliary calculi in vitro with low amplitude shock waves and verification by chemical dissolution]

In lowering the amplitude of pressure in the point of the shock-wave concentration under MPa (in our equipment by means of lowering discharge tension under 8 kV) macroscopically observable breakdown of stones in vitro after passage of 5 shock-waves will not occur in approximately 1/3 of bile stones. After effect of 5 shock-waves cholesterol elution in model solvents was accelerated. In exposed parts of stones the cholesterol concentration was in the 40th minute in methanol and perchlorethylene solution in 9:1 ratio 2.45 times higher on average. The stones were halved by a diamond knife. Only one half was exposed and the other one was used for comparison. From the study were eliminated such halves of stones that were macroscopically damaged after the shock-wave exposition where acceleration of cholesterol elution is a priori obvious.