High prevalence of cardiovascular co-morbidities in patients with symptomatic knee or hand osteoarthritis
J Calvet1,2, C Orellana1, M Larrosa1
1a Department of Rheumatology , Parc Taulí University Hospital , Sabadell , Spain.
Insights
Patients with osteoarthritis (OA) have a higher frequency of metabolic syndrome (MetS) and cardiovascular events (CVEs). This primary care study highlights the increased prevalence of these conditions in individuals with knee or hand OA.
Area of Science:
- Rheumatology
- Cardiology
- Metabolic Health
Background:
- Osteoarthritis (OA) is a prevalent degenerative joint disease.
- Cardiovascular events (CVEs) and metabolic syndrome (MetS) represent significant global health concerns.
- The association between OA and MetS/CVEs requires further investigation in primary care settings.
Purpose of the Study:
- To determine the frequency of cardiovascular events (CVEs) and metabolic syndrome (MetS) in patients with symptomatic knee or hand osteoarthritis (OA).
Main Methods:
- A cross-sectional study involving 254 OA patients and 254 controls in primary care.
- Data collected included hypertension, diabetes mellitus, obesity, dyslipidaemia, and CVEs (myocardial infarction, angina, cerebrovascular disease).
- Patients with soft tissue conditions served as the control group.
Main Results:
- Metabolic syndrome (MetS) was significantly more frequent in OA patients (overall, knee OA, and hand OA) compared to controls (p < 0.001).
- Odds ratios for MetS were 2.4 (OA group), 2.29 (knee OA), and 2.67 (hand OA).
- Higher prevalence of obesity, hypertension (in knee OA), and cardiovascular events (CVEs) were observed in OA patients versus controls.
Conclusions:
- Symptomatic osteoarthritis patients in primary care settings exhibit a high frequency of metabolic syndrome (MetS).
- A notable prevalence of cardiovascular events (CVEs) was also observed in this OA patient cohort.
- These findings underscore the importance of screening for MetS and CVEs in OA management.
Objectives:
To evaluate the frequency of cardiovascular events (CVEs) and metabolic syndrome (MetS) in patients with symptomatic knee or hand osteoarthritis (OA).
Method:
A cross-sectional study conducted by rheumatologists in a primary care setting. Consecutive symptomatic patients with primary knee or hand OA were included and patients with soft tissue conditions served as the control group. Hypertension, diabetes mellitus, obesity, dyslipidaemia, and CVEs consisting of myocardial infarction, angina, or cerebrovascular disease were recorded.
Results:
A total of 254 OA patients (184 with knee OA and 70 with hand OA) and 254 control patients were included. The frequency of obesity was higher in all OA groups and hypertension was more frequent in knee OA. MetS was significantly more frequent in patients with OA as a whole group and in knee or hand OA groups separately (p < 0.001, p = 0.002, and p = 0.007, respectively, vs. control group), with odds ratio (OR) 2.4, 95% confidence interval (CI) 1.26-4.55 in the OA group, OR 2.29, 95% CI 1.15-4.54 in the knee OA group, and OR 2.67, 95% CI 1.15-6.19 in the hand OA group. A higher prevalence of CVEs in the three OA groups was observed compared with the control group.
Conclusions:
A high frequency of MetS and CVEs was observed in OA patients in a primary care setting.
Related Concept Videos
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
01:24Chronic Kidney Disease II: Clinical Manifestations
01:30Coronary Artery Disease III: Clinical Manifestations
01:23Rheumatic Heart Disease I: Introduction
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests