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Building a staircase to precision medicine for biliary tract cancer
Nataliya Razumilava1, Gregory J Gores2
1Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA.
Abstract:
A new study has conducted a comprehensive exome and transcriptome analysis of a large number of intrahepatic, perihilar and distal cholangiocarcinomas and gallbladder cancers in Japanese patients. This study identifies many new alterations, confirms genetic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately 40% of described genetic aberrations are potentially targetable.
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