Related Experiment Video
Updated: Apr 4, 2026

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
Published on: March 23, 2018
Patient blood management to reduce surgical risk
B Clevenger1,2, S V Mallett1,2, A A Klein3
1Division of Surgery and Interventional Science, University College London, London, UK.
Preoperative anemia and blood transfusions are significant surgical risks. Patient blood management (PBM) optimizes patient care by treating anemia, reducing blood loss, and using restrictive transfusion triggers, improving surgical outcomes.
Area of Science:
- Anesthesiology
- Surgical Care
- Hematology
Background:
- Preoperative anemia and perioperative blood transfusion are significant, preventable surgical risks.
- Patient blood management (PBM) is a multimodal strategy addressing these risks.
- PBM focuses on treating anemia, reducing blood loss, and optimizing patient reserves.
Purpose of the Study:
- To review the necessity of PBM in surgical pathways.
- To outline strategies for PBM implementation.
Main Methods:
- Literature search of studies on PBM's three pillars using PubMed.
- Focus on recent evidence-based guidance for perioperative management.
Main Results:
- Anemia is prevalent in surgical patients, independently linked to adverse outcomes.
- Intravenous iron is recommended for functional iron deficiency; tranexamic acid and cell salvage reduce intraoperative blood loss.
- Restrictive transfusion practices are the standard of care post-surgery.
Conclusions:
- Preoperative anemia is often underappreciated and requires routine investigation and treatment.
- The risks of unnecessary blood transfusions are increasingly recognized.
- Adopting PBM in surgical practice is recommended to reduce costs and enhance patient outcomes.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Pre-Procedural Guidelines for Assessing Blood Pressure
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Venous Thrombosis IV: Nursing Management
Aneurysm IV: Nursing Management
Errors occurring during blood pressure monitoring
Several factors...

