Precise correlation between structural and electrophysiological disturbances in MADSAM neuropathy
Neil G Simon1, Matthew C Kiernan2
1Brain and Mind Research Institute, Sydney Medical School, The University of Sydney, Australia; Prince of Wales Clinical School, University of New South Wales, Australia.
Neuromuscular Disorders : NMD
|August 29, 2015
Summary
Multifocal acquired demyelinating sensory and motor neuropathy shows nerve enlargements that correlate with conduction block. This study links structural nerve changes to electrophysiological dysfunction in this rare neuropathy.
Area of Science:
- Neurology
- Neurophysiology
- Medical Imaging
Background:
- Multifocal acquired demyelinating sensory and motor neuropathy presents with varied clinical deficits.
- Previous imaging identified multifocal nerve enlargements, but structural-functional correlation is unclear.
Keywords:
Chronic inflammatory demyelinating polyradiculoneuropathyConduction blockMADSAMPathophysiologyUltrasound

