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Related Concept Videos

Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

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Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
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Oral Hypoglycemic Agents: α-Glucosidase Inhibitors01:19

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
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Oral Hypoglycemic Agents: Glinides01:06

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Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
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SBAR II: Application of SBAR01:14

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
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Diabetes Mellitus: Type 2 and Gestational01:22

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Serum Laboratory Studies, Stool Test, Breath Test01:30

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Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
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Related Experiment Video

Updated: Apr 4, 2026

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
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Diagnostic tools for post-gastric bypass hypoglycaemia.

M Emous1, F L Ubels2, A P van Beek1,3

  • 1Department of Bariatric and Metabolic Surgery, Medical Center Leeuwarden, Leeuwarden, The Netherlands.

Obesity Reviews : an Official Journal of the International Association for the Study of Obesity
|August 29, 2015
PubMed
Summary
This summary is machine-generated.

Diagnosing post-gastric bypass hypoglycemia lacks clear guidelines. This study reviews diagnostic tests, highlighting the need for validated tools to accurately identify this complication after gastric bypass surgery.

Keywords:
Diagnosisgastric bypasshypoglycaemia

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Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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Area of Science:

  • Bariatric Surgery
  • Endocrinology
  • Gastroenterology

Background:

  • Late complications, including post-gastric bypass hypoglycemia, can occur after gastric bypass surgery.
  • No evidence-based guidelines currently exist for diagnosing post-gastric bypass hypoglycemia.

Purpose of the Study:

  • To describe and compare diagnostic tests for post-gastric bypass hypoglycemia.
  • To propose a diagnostic approach based on available evidence.

Main Methods:

  • Literature search conducted in PubMed, Cochrane, and Embase databases.
  • Evaluation of existing questionnaires and provocation tests for diagnosing post-gastric bypass hypoglycemia.

Main Results:

  • Several questionnaires exist but lack validation for measuring post-gastric bypass hypoglycemia symptom severity.
  • Oral glucose tolerance tests and mixed meal tolerance tests show high hypoglycemia prevalence in various patient groups.
  • No standardized glucose concentration cut-off values are established for diagnosis.

Conclusions:

  • A validated questionnaire combined with provocation test performance is crucial for accurate diagnosis.
  • Recommendations for diagnosing post-gastric bypass hypoglycemia are provided based on current literature.