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Related Concept Videos

Olfactory Receptors: Location and Structure01:03

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The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Related Experiment Video

Updated: Apr 4, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Olfactory Neuroblastoma: A Case Report.

Heather R Olmo1, Steven Marc Stokes2, Robert D Foss3

  • 1Office of The Surgeon General, US Army, Dental Corps, 7700 Arlington Blvd., Falls Church, VA, 22042, USA. heather.r.olmo.mil@mail.mil.

Head and Neck Pathology
|August 29, 2015
PubMed
Summary
This summary is machine-generated.

A persistent nasal mass caused a 43-year-old female

Keywords:
Flexner-Wintersteiner rosettesHomer Wright pseudorosettesNasal cavityOlfactory neuroblastomaParanasal sinusesRadiology

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Area of Science:

  • Otorhinolaryngology
  • Oncology
  • Pathology

Background:

  • Olfactory neuroblastoma is a rare malignant tumor arising from the olfactory epithelium.
  • Early diagnosis is crucial for effective management and improved patient outcomes.

Observation:

  • A 43-year-old female presented with chronic nasal congestion and epistaxis.
  • Clinical examination revealed a large nasal mass extending to the choana.
  • Radiographic imaging showed a lobular soft tissue mass with orbital and ethmoid sinus involvement.

Findings:

  • The case highlights the clinical, radiographic, histologic, and immunohistochemical features of olfactory neuroblastoma.
  • Diagnostic challenges associated with differentiating this rare tumor from other sinonasal masses.

Implications:

  • This case underscores the importance of thorough evaluation for persistent sinonasal symptoms.
  • Accurate diagnosis of olfactory neuroblastoma is critical for appropriate treatment planning and prognosis.
  • Further research into early detection methods for olfactory neuroblastoma is warranted.