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Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy
Kazuma Kobayashi1, Naoya Murakami1, Akihisa Wakita1
1Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
Abstract:
We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose-volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.
