Adherence to diabetes guidelines for screening, physical activity and medication and onset of complications and death
Yiqun Chen1, Frank A Sloan1, Arseniy P Yashkin1
1Department of Economics, Duke University, 213 Social Sciences Building, Box 90097, Durham, NC, 27708.
Insights
Adhering to diabetes care guidelines, including regular screening, physical activity, and medication, significantly reduces the risk of complications and mortality in older adults. These healthy habits are crucial for managing diabetes and improving long-term outcomes.
Area of Science:
- Gerontology
- Public Health
- Endocrinology
Background:
- Diabetes care guidelines aim to prevent complications and improve outcomes.
- Adherence to these guidelines is variable and its impact on long-term health in older adults requires investigation.
Purpose of the Study:
- To analyze the relationship between adherence to diabetes care guidelines (screening, physical activity, medication) and the risk of diabetes-related complications and mortality.
- To assess the impact of adherence on specific outcomes such as congestive heart failure, stroke, renal failure, lower extremity complications, amputations, retinopathy, and overall mortality.
Main Methods:
- Utilized data from the Health and Retirement Study (HRS) 2003 Diabetes Study, focusing on individuals aged 65+ with Medicare claims.
- Examined outcomes including congestive heart failure (CHF), stroke, renal failure, lower extremity complications, lower-limb amputation, proliferative diabetic retinopathy (PDR), and mortality between 2004-2008.
Main Results:
- Adherence to screening guidelines reduced risks of CHF, stroke, renal failure, and death.
- Physical activity adherence lowered risks of stroke, renal failure, lower extremity complications, amputation, and death.
- Medication adherence was linked to a reduced risk of proliferative diabetic retinopathy (PDR).
Conclusions:
- Adherence to screening, physical activity, and medication guidelines is associated with significantly lower risks of diabetes complications and mortality in older adults.
- The relative importance of adherence to specific guidelines varies depending on the outcome measure.
Aims:
Analyze relationships between adherence to guidelines for diabetes care - regular screening; physical activity; and medication - and diabetes complications and mortality.
Methods:
Outcomes were onset of congestive heart failure (CHF), stroke, renal failure, moderate complications of lower extremities, lower-limb amputation, proliferative diabetic retinopathy (PDR), and mortality during follow-up. Participants were persons aged 65+ in the Health and Retirement Study (HRS) 2003 Diabetes Study and had Medicare claims in follow-up period (2004-8).
Results:
Adherence to screening recommendations decreased risks of developing CHF (odds ratio (OR)=0.83; 95% confidence interval (CI): 0.72-0.96), stroke (OR=0.80; 95% CI: 0.68-0.94); renal failure (OR=0. 82; 95% CI: 0.71-0.95); and death (OR=0.86; 95% CI: 0.74-0.99). Adherence to physical activity recommendation reduced risks of stroke (OR=0.64; 95% CI: 0.45-0.90), renal failure (OR=0.71; 95% CI: 0.52-0.97), moderate lower-extremity complications (OR=0.71; 95% CI: 0.51-0.99), having a lower limb amputation (OR=0.31, 95% CI: 0.11-0.85), and death (OR=0.56, 95% CI: 0.41-0.77). Medication adherence was associated with lower risks of PDR (OR=0.35, 95% CI: 0.13-0.93).
Conclusions:
Adherence to screening, physical activity and medication guidelines was associated with lower risks of diabetes complications and death. Relative importance of adherence differed among outcome measures.
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