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Cohort Study: Central Venous Catheter-Related Complications in Children with Hematologic Diseases at a Single Center

Ayhan Pektaş1, Ateş Kara, Aytemiz Gurgey

  • 1Afyon Kocatepe University Faculty of Medicine Hospital, Department of Pediatrics, Afyonkarahisar, Turkey Phone: +90 (272) 246 33 33

Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
|August 29, 2015
PubMed

Insights

Central venous catheter (CVC) complications in pediatric hematology patients were analyzed. Leukemia, bone marrow transplantation, and thrombocytopenia were identified as risk factors for CVC-associated issues.

Area of Science:

  • Pediatric Hematology
  • Infectious Diseases
  • Vascular Access Devices

Background:

  • Central venous catheters (CVCs) are crucial for treating pediatric patients with hematological diseases.
  • Understanding CVC-related complications is vital for patient safety and treatment efficacy.

Purpose of the Study:

  • To document and analyze central venous catheter (CVC)-related complications in children with hematological diseases.
  • To identify specific risk factors associated with CVC complications in this vulnerable population.

Main Methods:

  • Retrospective investigation of 106 pediatric patients.
  • Analysis of 203 CVC insertions over a 5-year period.
  • Documentation of 175 catheter-related complications.

Main Results:

  • Overall complication rates per 1000 catheter days: clinical infections (2.6), local infections (1.1), venous thromboembolism (0.2), bleeding (0.2), mechanical complications (0.2).
  • Methicillin-resistant Staphylococcus epidermidis was the predominant infectious organism.
  • Leukemia, thrombocytopenia, and bone marrow transplantation were associated with increased CVC complications; implanted catheters showed lower infection rates.

Conclusions:

  • Leukemia, bone marrow transplantation, and thrombocytopenia are significant risk factors for CVC-associated complications.
  • Implanted catheters may be associated with a higher incidence of systemic infections and mechanical injury due to increased interventions.
Abstract

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