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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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Ophthalmic regional blocks: management, challenges, and solutions.

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Summary

Ophthalmic anesthesia has shifted from general to regional and topical anesthesia for eye surgeries. Anesthesiologists need enhanced training in eye blocks to improve efficiency and manage patient needs.

Keywords:
anticoagulationhyaluronidaseocular traumaophthalmic anesthesiaultrasoundvenous air embolism

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Area of Science:

  • Anesthesiology
  • Ophthalmology

Background:

  • Ophthalmic anesthesia has transformed, moving from general anesthesia in hospitals to regional and topical anesthesia in eye care centers.
  • The growing elderly population necessitates efficient surgical practices, driving demand for improved anesthetic techniques.

Purpose of the Study:

  • To review current trends and topical issues in ophthalmic anesthesia.
  • To emphasize needle-based and cannula blocks, new antithrombotic agents, and ultrasound guidance.

Main Methods:

  • Review of current literature on ophthalmic anesthesia techniques.
  • Discussion of regional block advancements, including sub-Tenon's and peribulbar approaches.
  • Exploration of adjuncts like hyaluronidase and the role of ultrasound guidance.

Main Results:

  • Sub-Tenon's block is gaining popularity, while retrobulbar blocks are less common.
  • Phacoemulsification enables topical anesthesia for cataract surgery.
  • Ultrasound guidance enhances safety by visualizing needle placement and anatomy, reducing risks like globe perforation.

Conclusions:

  • Anesthesiologists require updated training in ophthalmic regional blocks to meet evolving surgical demands and economic pressures.
  • Ultrasound-guided blocks offer improved safety and efficiency in ophthalmic anesthesia.
  • The shift towards regional and topical anesthesia reflects advancements in surgical techniques and anesthetic practices.