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In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
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Application of a biotin-labelled DNA probe to detect Campylobacter

Y T Zhou1, S Q Wang

  • 1Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing.

Zentralblatt Fur Bakteriologie : International Journal of Medical Microbiology
|December 1, 1989
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...