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Intrathecal meperidine as the sole agent for cesarean section
1Department of Anesthesiology, College of Medicine, Keimyung University, Taegu, Korea.
Journal of Korean Medical Science
|September 1, 1989
Summary
Meperidine can be a safe and effective sole agent for spinal anesthesia during Cesarean sections, offering prolonged pain relief and quick motor recovery with manageable side effects.
Area of Science:
- Anesthesiology
- Obstetric Anesthesia
Background:
- Meperidine is increasingly recognized for its utility as a sole spinal anesthetic agent.
- Previous reports highlight its potential in various surgical contexts.
Purpose of the Study:
- To evaluate meperidine as a sole spinal anesthetic agent for Cesarean sections.
- To assess its efficacy, safety, and side effect profile in this specific obstetric procedure.
Main Methods:
- 182 Cesarean sections were performed using meperidine (50mg) mixed with 10% dextrose (0.5ml) for spinal anesthesia.
- Sensory and motor blockade, duration of analgesia, motor recovery time, and Apgar scores were recorded.
Main Results:
- Meperidine provided anesthesia comparable to local anesthetics, achieving sensory and motor blockade in all patients.
- Prolonged analgesia (453.7 ± 158.1 min) and rapid motor recovery (75.9 ± 17.2 min) were observed.
- Common side effects included nausea (26.9%), hypotension (52.2%), and pruritus (16.5%), which were generally manageable.
Conclusions:
- Meperidine serves as a viable alternative for spinal anesthesia in Cesarean sections.
- Its advantages include rapid motor recovery, extended postoperative analgesia, and a profile of mild, treatable complications.