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Maternal Microbiome and Pregnancy Outcomes That Impact Infant Health: A Review

Anne L Dunlop1, Jennifer G Mulle, Erin P Ferranti

  • 1Emory University School of Nursing, Atlanta, Georgia (Dr Dunlop); Department of Human Genetics, Rollins School of Public Health and School of Medicine, Emory University, Atlanta, Georgia (Dr Mulle); and Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia (Dr Ferranti, Ms Edwards, Ms Dunn, and Dr Corwin).

Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses
|August 29, 2015
PubMed

Insights

The maternal microbiome significantly impacts pregnancy outcomes and infant health. Research explores its role in adverse conditions and strategies for promoting a healthy maternal gut microbiome.

Area of Science:

  • Microbiology
  • Maternal-fetal medicine
  • Public health

Background:

  • The maternal microbiome is crucial for maternal and infant health.
  • It influences the infant microbiome alongside perinatal factors.
  • Dysbiosis is linked to adverse pregnancy outcomes.

Purpose of the Study:

  • Review the maternal microbiome's role in adverse pregnancy outcomes.
  • Identify factors influencing maternal microbiome composition.
  • Explore strategies for a healthy maternal microbiome.

Main Methods:

  • Literature review of existing research.
  • Synthesis of findings on maternal microbiome and pregnancy.
  • Identification of knowledge gaps and future research directions.

Main Results:

  • Maternal microbiome influences preterm birth, preeclampsia, gestational diabetes, and excessive gestational weight gain.
  • Factors like diet and lifestyle impact maternal microbiome composition.
  • Limited but emerging strategies exist for promoting a healthy maternal microbiome.

Conclusions:

  • The maternal microbiome is a critical factor in pregnancy success.
  • Further research is essential to understand and modulate the maternal microbiome for improved outcomes.
  • Targeting the maternal microbiome offers potential for enhanced maternal and child health.

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