Reliability and validity of the Manual Ability Measure-36 in persons with Charcot-Marie-Tooth disease
Janet L Poole1, Matthew Huffman2, Anaclaire Hunter3
1University of New Mexico, Occupational Therapy Graduate Program, Albuquerque, NM, USA.
Study Design:
Descriptive, clinical measurement.
Introduction:
Charcot-Marie-Tooth disease (CMT) is a genetic disorder that results in demyelination or axonal degeneration in peripheral nerves. Characteristic symptoms include decreased muscle strength and sensation, particularly in the hands and feet.
Purpose:
Examine the reliability and validity of the Manual Ability Measure (MAM-36), a 36-item self-report questionnaire specific to hand function, in persons with CMT.
Methods:
Fourteen participants with CMT completed the MAM-36 at two points one week apart. Participants were also administered performance-based tests for grip and pinch strength, dexterity, and sensation.
Results:
The test-retest intraclass correlation coefficient (ICC) for the MAM-36 was 0.96. Pearson correlation coefficients showed fair to good relationships (r = 0.41-0.64) between the MAM-36 scores and most of the performance tests.
Conclusion:
The MAM-36 is a reliable and valid assessment tool for measuring hand function during everyday tasks in persons with CMT.
Level Of Evidence:
IIb.
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