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Solving the chemical master equation by a fast adaptive finite state projection based on the stochastic simulation

R B Sidje1, H D Vo1

  • 1Department of Mathematics, The University of Alabama, Tuscaloosa, AL 35487, USA.

Mathematical Biosciences
|August 31, 2015
PubMed
Summary

The chemical master equation (CME) models cell reactions but is hard to solve. This study introduces a new method using the stochastic simulation algorithm (SSA) to improve the finite state projection (FSP) approach for better computational efficiency.

Keywords:
Chemical master equationFinite state projectionMatrix exponentialModel reductionStochastic simulation algorithm

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