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Updated: Aug 30, 2026

In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint
Published on: March 7, 2014
Collagen phagocytosis by cementoblasts at the periodontal ligament-cementum interface
1Department of Oral Anatomy, Higashi-Nippon-Gakuen University School of Dentistry, Hokkaido, Japan.
Abstract:
The periodontal ligament-cementum interface of rat first molars was investigated by electron microscopy. Evidence supporting cementoblast phagocytosis of collagen fibrils of the periodontal ligament was found. In addition, collagen-containing vacuoles were frequently observed within cementoblasts in association with an acid phosphatase activity. The presence of acid phosphatase activity in these vacuoles suggested that intracellular degradation of collagen was occurring. Our results showed that cementoblasts exhibited collagen phagocytic activity and suggest that cementoblasts may play an important role in the physiological remodeling and metabolic breakdown of the collagen at the periodontal ligament-cementum interface.
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