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Electron Transport Chain: Complex I and II

Electron Transport Chain: Complex I and II

The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...

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Related Experiment Video

Updated: Apr 4, 2026

Isolation and Functional Analysis of Mitochondria from Cultured Cells and Mouse Tissue

Isolation and Functional Analysis of Mitochondria from Cultured Cells and Mouse Tissue

Published on: March 23, 2015

Methylene blue, a potential therapeutic target for mitochondria dysfunction

Xiang Lin¹, Bing Bing Wu¹, Qun Ya Xing¹

¹The Second Affiliated Hospital of Bengbu Medical College, Bengbu 233040, China.

International Immunopharmacology

|August 31, 2015

Summary

No abstract available in PubMed .

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