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Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
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Basic principles of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS)
Wanalee Klomjai1, Rose Katz2, Alexandra Lackmy-Vallée3
1Faculty of Physical Therapy, Mahidol University, 73170 Nakonpathom, Thailand.
Annals of Physical and Rehabilitation Medicine
|August 31, 2015
Summary
Transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS) are non-invasive brain stimulation techniques. This review summarizes their mechanisms, parameters, and clinical applications for neurological and psychiatric conditions.
Area of Science:
- Neuroscience
- Neuromodulation
- Cognitive Science
Background:
- Transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS) are non-invasive brain stimulation techniques.
- These methods use magnetic fields to modulate motor cortex excitability.
- rTMS shows potential for inducing brain plasticity and therapeutic effects.
Purpose of the Study:
- To review current knowledge on TMS and rTMS mechanisms of action.
- To identify parameters influencing TMS/rTMS effects.
- To inventory common rTMS paradigms and hypotheses for after-effects.
Main Methods:
- Literature review of TMS and rTMS studies.
- Analysis of existing research on neurophysiological effects.
- Inventory of clinical research paradigms and theoretical models.
Main Results:
- TMS is crucial for investigating human brain function.
- rTMS demonstrates potential for inducing long-lasting brain plasticity.
- Mechanisms of action for TMS/rTMS effects require further clarification.
Conclusions:
- Understanding TMS/rTMS mechanisms is essential for optimizing therapeutic applications.
- Further research is needed to elucidate the precise physiological underpinnings of TMS/rTMS.
- rTMS holds promise as a therapeutic tool for neurological and psychiatric disorders.
