Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Bone changes in tuberous sclerosis (Bourneville-Pringle disease)].

B Kreuzberg, J Koudelková

    Ceskoslovenska Radiologie
    |October 1, 1989
    PubMed
    Summary

    Tuberous sclerosis, a rare genetic disorder, often presents with epilepsy, intellectual disability, and skin lesions. Bone changes, though common and asymptomatic, can mimic metastases, complicating diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Neuroendocrine adenoma of the middle ear with extension into the external auditory canal.

    Ceskoslovenska patologie·2012
    Same author

    [Portal vein branch embolization in patients with primary inoperable liver tumors].

    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2010
    Same author

    [Laparoscopic adrenalectomy].

    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2010
    Same author

    Diagnostic problems of abdominal desmoid tumors in various locations.

    European journal of radiology·2007
    Same author

    [Massive breast angiomatosis with dramatic course leading to acute total mastectomy--a case report].

    Ceska gynekologie·2006
    Same author

    [Giant bilateral adrenal myelolipoma associated with congenital adrenal hyperplasia].

    Zentralblatt fur Chirurgie·2006

    Area of Science:

    • Neurology
    • Genetics
    • Dermatology

    Background:

    • Tuberous sclerosis is a rare hereditary disorder.
    • Classic symptoms include epilepsy, intellectual disability, and adenoma sebaceum.
    • Atypical presentations occur in 50% of cases, lacking neurological or skin findings.

    Observation:

    • Bone changes are asymptomatic and found in up to 50% of patients.
    • These bone changes can be misdiagnosed as osteoplastic metastases.
    • A specific case highlights this diagnostic challenge.

    Findings:

    • Asymptomatic bone changes in tuberous sclerosis can mimic other conditions.
    • Cranial calcifications are typical findings on brain imaging.
    • Knowledge of these bone manifestations aids differential diagnosis.

    Implications:

    • Recognizing bone changes in tuberous sclerosis is crucial for accurate diagnosis.
    • Computer tomography of the brain can reveal characteristic calcifications.
    • This aids in differentiating tuberous sclerosis from other pathologies like metastases.

    Related Experiment Videos