[On "2015 Guidelines for Prevention and Treatment of Osteoporosis". CKD and osteoporosis]

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Shinsuke Yamada1, Masaaki Inaba

  • 1Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan.

Clinical Calcium
|September 1, 2015
PubMed

Insights

Patients with chronic kidney disease (CKD) face a higher risk of fractures due to osteoporosis. Established osteoporosis treatments are often unsuitable for CKD patients, necessitating careful medical management.

Area of Science:

  • Nephrology
  • Endocrinology
  • Geriatrics

Context:

  • Osteoporosis is a common comorbidity in patients with chronic kidney disease (CKD).
  • Patients with both osteoporosis and CKD exhibit an elevated risk of hip and vertebral fractures compared to those with osteoporosis alone.
  • Renal excretion of osteoporosis medications poses challenges for treatment efficacy and safety in CKD patients.

Purpose:

  • To outline the intricate relationship between chronic kidney disease and osteoporosis.
  • To highlight critical considerations for managing osteoporosis in patients with concurrent CKD.

Summary:

  • This review details the association between CKD and osteoporosis, emphasizing the increased fracture risk in this patient population.
  • It addresses the therapeutic gap, as standard osteoporosis drugs are often not established as safe or effective for individuals with impaired kidney function.
  • Key aspects of medical care for osteoporosis patients with CKD are discussed.

Impact:

  • Provides essential insights for clinicians managing patients with comorbid osteoporosis and CKD.
  • Highlights the need for specialized treatment strategies and further research into safe and effective osteoporosis therapies for CKD patients.
  • Aims to improve fracture prevention and patient outcomes in this vulnerable group.

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